- 80% of patients with inactive HBV have detectable low level DNA, usually < 500,000 copies/mL
- Patients with normal LFT, E antibody positive & low level DNA should still be considered to have inactive disease and should not be Rxed
- HBV Genotypes
- 7% A (Best response to IF)
- 27% B
- 51% C
- 15% D
- Genotyping will become important to determine candidates for IF vs antiviral Rx
- Peg IF
- Lamivudine, Adefovir, Entecovir, Ldt
- HBV resistance testing will become important with introduction of new antiviral medications
|
