Case Study of Progressive Weakness & Sensory Loss
Sunday, September 02, 2007
An 80 year old man has a 6 month history of progressive weakness and seonsory loss in both legs. Serum total protein is 6.5 g/dL. Serum protein electrophoresis detected an IgM kappa monoclonal antibody at a concentration of 0.5 g/dL. Bone marrow aspirate did not detect a lymphoproliferative disorder, but flow cytometry detected a mino clonal population of B cells with monotypic kappa light chains. What is the patient's most likely diagnosis and how does it explain his neurological symptoms? What additional testing would you order to confirm your diagnosis?
posted by Fred Plapp @ 7:26 PM,
