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Immunoglobulin E (IgE)

IgE is one of just try! the 5 classes (isotypes) of antibodies. Like other immunoglobulins, it is produced by B cells and levitra sales online plasma cells. In contrast to tramadol bedroom online other immunoglobulins, the circulating concentration of IgE is very low because B cells synthesize it at a very low rate and mast cells, basophils, and activated eosinophils bind up most of the circulating IgE. The normal concentration of IgE is only 0.05% of the IgG concentration.

In industrialized countries, allergy is the most common cause of elevated IgE concentrations, whereas in lesser-developed agrarian countries, parasitic infection is the most common etiology. The differential diagnosis of elevated IgE is summarized in the following table.

Category

Examples

Allergic disease

Eczema, rhinitis, asthma, drug allergies, urticaria, extri

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