1. Skip to Menu
  2. Skip to Content
  3. Skip to Footer

Jo1 Antibody

The Jo-1 antigen resides on the enzyme, histidyl-tRNA synthetase, which is usually located in the cytoplasm of cells, rather than the nucleus. Antibodies to the Jo-1 antigen are detected in approximately 25% of adult patients with myositis including; polymyositis, dermatomyositis, and overlap syndromes. Jo-1 antibodies are most commonly found in patients (68%) with a combination of myositis and interstitial pulmonary fibrosis. Patients with Jo-1 antibodies may have a negative ANA, for the same reasons described for SS-A/Ro antibodies.

Specimen requirement is one red top tube of blood.

AddThis Social Bookmark Button

Stay Informed

Amazon Book

Our Sponsors

Login Form

Mobile Applications

iPad mini Horz Vert 300w

Get it for: iPhoneiPad

ClinLab Navigator Information

McAfee SECURE sites help keep you safe from identity theft, credit card fraud, spyware, spam, viruses and online scams
© 2015 ClinLab Navigator, LLC.