- Last Update On : 2014-07-13
Follwing thyroidectomy for thyroid cancer, approximately 10% of patients have tumor recurrence within the first 10 years after surgery and www.ostrodaonline.pl an additional 5% have an even later recurrence. Thyroglobulin (Tg) is a large glycoprotein that is synthesized in thyroid follicles and serves as the precursor of thyroid hormone (T4). Measurement of serum Tg is primarily used to detect recurrence of follicular thyroid cancer. Serum concentration reflects the sum of Tg from normal thyroid tissue and an residual or recurrent tumor.
A preoperative serum Tg level has no diagnostic or prognostic significance by itself, but does document that Tg can be followed postoperatively as a tumor marker for that patient. Preoperative specimens should either be drawn before fine needle aspirate (FNA) or more than 3 weeks following FNA. The sensitivity of postoperative serum Tg is highest when the tumor is relatively small (2 cm or less) and the canada cialis levitra preoperative serum Tg value is hig