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Clinical Laboratory



A Clinical laboratory is staffed by clinical pathologists, clinical laboratory scientists, medical laboratory technicians and support personnel, all of whom help the clinical laboratory play a vital role across the entire continuum of health care. Clinical laboratory testing has a major effect on clinical decision making by providing physicians, nurses and other health care providers with important information that is needed for the prevention, diagnosis, treatment and management of disease. Nearly every practicing physician depends upon a physician laboratory and clinical laboratory for the care of his or her patient.   A comprehensive and practical resource for physicians, laboratory professionals, and patients, ClinLab Navigator.com offers hundreds of up-to-date clinical laboratory test interpretations, test utilization algorithms, and transfusion guidelines using our article download service and affordable subscription plans.

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Updated Articles
ADAMTS13
January 31, 2012
In 1982, Moake discovered that patients with relapsing acquired or congenital TTP had unusually large multimers of von Willebrand Factor (VWF) circulating in their plasma. He proposed that TTP patients lacked a VWF protease that normally cleaved ultra:large VWF to prevent it from causing intravascular platelet aggregation and thrombosis. In 1996, VWF:cleaving protease was identified in human plasma and the following year VWF:cleaving protease was shown to be missing from the plasma of patients with congenital TTP. Soon after, adults with acquired idiopathic TTP were reported to have severe…
New Articles
Listeria Monocytogenes
January 02, 2012
Listeriosis is caused by Listeria monocytogenes, a gram-positive bacillus common in the environment and acquired by humans primarily through consumption of contaminated food. Infection causes a spectrum of illness, ranging from febrile gastroenteritis to invasive disease, including sepsis and meningoencephalitis. Invasive listeriosis occurs predominantly in older adults and persons with impaired immune systems. Listeriosis in pregnant women is typically a mild "flu-like" illness, but can result in fetal loss, premature labor, or neonatal infection. Listeriosis is treated with antibiotics.  …
Blog
Coagulation Disorders Associated with Liver Failure
September 05, 2011
The liver is the major site of synthesis of almost all coagulation factors, except for Factor VIII and vWF. Liver failure is associated with decreased coagulation factors, decreased or dysfunctional platelets, dysfibrinogenemia and fibrinolysis. Patients with severe liver disease have lower levels of those coagulation factors synthesized by the liver. Inadequate vitamin K absorption may occur as a result of decreased bile acid secretion into the intestine, leading to a reduction in coagulation factors II, VII, IX and X. Abnormal forms of fibrinogen may be produced causing dysfibrinogenemia.…
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April 20, 2011
If you’ve discovered the convenience and value of ClinLab Navigator’s article download services, consider purchasing one of time and money-saving subscriptions packages and you’ll never be at a loss for an answer or critical information again. Packages ranging from month-to-month, six months or annual, and with them, you’ll gain unlimited access to our database of industry-leading articles and information. Professional knowledge and expertise will be at your fingertips 24 hours a day, seven days a week. No waiting, no hassle—just important information to aid today’s busy laboratory…