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Carcinoembryonic Antigen (CEA)

CEA is a large family of 36 different, but related, glycoproteins, which are part of viagra order uk the immunoglobulin superfamily. The human CEA gene family is clustered on chromosome 19q and comprises 29 genes. Seven of these 29 genes code for CEA glycoproteins. CEA molecules exhibit considerable heterogeneity due to variation in carbohydrate side chains.

CEA is present in the gastrointestinal tract during fetal life and canada prescriptions levitra occurs at low concentrations in adults. CEA was first reported to be quite specific for tumors of the GI tract, but further investigations demonstrated elevations in several other malignant and benign diseases. Elevated CEA levels are suggestive, but not diagnostic of cancer, since elevated levels also occur in a variety of benign conditions:

  • Most normal persons have detectable concentrations of circulating CEA. Approximately 85% of adults have CEA levels less than 2.5 ng/mL, while 95% have levels less than 5.0 ng/mL. CEA levels are slightly higher in men

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