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Islet Cell Antibodies

Type 1 diabetes mellitus (T1D) is an autoimmune disease that results from the cell-mediated destruction of islet beta cells. Approximately 12,000 to 15,000 children and adults annually develop T1D. The most recent Standards of Medical Care in…

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FLT3 Mutation

Fms-like tyrosine kinase 3 (FLT3) is a receptor tyrosine kinase that is expressed on hematopoietic progenitor cells and plays a crucial role in hematopoiesis. FLT3 mutations lead to constitutive activation of the FLT3 receptorThere are 2 major…

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Repeat Lipase Testing

The American Society of Clinical Pathology recommends measuring lipase for the initial diagnosis of acute pancreatitis, but states that repeat measurements have little value. There is no evidence that the degree of lipase elevation predicts severity…