- Last Update On : 2013-01-29
Prevention of Hemolytic Disease of the Newborn Due to Anti-D Routine testing and appropriate use of Rh Immune Globulin (RhIG) during pregnancy and immediately after delivery or termination of pregnancy can successfully prevent most cases of hemolytic disease of the newborn (HDN) caused by alloimmunization to the D antigen. RhIg timing and dosage depend on the gestational date and on whether any events that increase the risk of fetomaternal hemorrhage (FMH) have occurred. Antepartum administration of Rho Immune Globulin (RhIG) is indicated between 26 and 28 weeks of gestation in all pregnant Rh negative women who have not already developed anti-D. RhIG is also recommended after invasive procedures such as amniocentesis, periumbilical blood sampling (PUBS), intrauterine transfusions, pregnancy termination, amniocentesis or other obstetrical complications.
Prenatal/Perinatal Testing and Rh Immune Globulin Administration I. Initial visit All women should have ABO and D te