Clinlab Navigator

Jamestown Canyon Virus

Jamestown Canyon Virus is transmitted to people by infected mosquitos. Mosquitos become infected when they feed on infected deer. The virus is found throughout much of the United States, but Minnesota and Wisconsin have reported more than half of the cases. Most infections occur between April and September. 

The time from mosquito bite to development of symptoms ranges from a few days to 2 weeks. Initial symptoms can include fever, fatigue, and headache. Jamestown Canyon Virus can cause encephalitis. Approximately half of infected people are hospitalized but deaths are rare. Approximately 17 neuroinvasive cases are reported each year. 

Diagnosis is usually made by testing for Jamestown Canyon virus-specific IgM antibody M followed by a confirmatory plaque reduction neutralization test (PRNT). 

References

Patriquin G, Drebot M, Cole Teri, et al. High seroprevalence of Jamestown Canyon virus among deer and humans, Nova Scotia, Canada. Emerg Infect Dis 2018;24:118‒121.

Pastula DM, Hoang Johnson DK, White JL, Dupuis AP, Fischer M, Staples JE. Jamestown Canyon virus disease in the United States — 2000–2013. Am J Trop Med Hyg 2015;93:384–389.

Updated Articles

Herpes Simplex Virus…

Humans are the only natural reservoir of herpes simplex virus (HSV) type 1 (HSV-1) and type 2 (HSV-2). HSV is one of the most prevalent viral infections in the world. Genital herpes is a sexually transmitted disease caused by either HSV-1 or HSV-2.…

New Articles

VEXAS Syndrome

VEXAS syndrome is a rare disease that causes late onset recurrent episodes of inflammation and hematologic abnormalities in men over the age of 50. Clinical manifestations of VEXAS syndrome are variable and include skin lesions, recurrent fever,…

Blog

Laboratory Tests for…

Cirrhosis is defined as the fibrotic replacement of liver tissue that can result from any chronic liver disease. Cirrhosis affects approximately 2.2 million adults in the United States and is associated with mortality rates of 21.9 per 100 000…